Table 4. Difference in the scores of BASDAI, BASFI, and BAS-G among AS patients stratified by rs4552569 and rs17095830 genotypes.
| SNP | Genotype | BASDAI | BASFI | BAS-G |
| rs4552569 | CC | 4.89±1.92 | 2.24±2.05 | 4.38±2.46 |
| CT | 4.34±2.22 | 2.07±2.22 | 4.52±2.79 | |
| TT | 4.20±2.20 | 2.01±2.18 | 4.27±2.75 | |
| Unadjusted P-value | 0.2393 | 0.8297 | 0.6436 | |
| Adjusted P-value | 0.2387† | 0.7625§ | 0.6405† | |
| rs17095830 | GG | 3.91±3.23 | 2.93±4.39 | 4.12±4.62 |
| AG | 4.62±2.22 | 2.09±2.08 | 4.58±2.94 | |
| AA | 4.26±2.18 | 2.04±2.19 | 4.36±2.68 | |
| Unadjusted P-value | 0.3610 | 0.6202 | 0.7779 | |
| Adjusted P-value | 0.3602† | 0.9494§ | 0.7757† | |
| Two-locus model | ||||
| High-risk group | 4.34±2.19b | 2.17±2.28b | 4.49±2.94b | |
| Low-risk group | 4.01±2.17b | 2.02±2.17b | 4.36±2.71b | |
| Unadjusted P-value | 0.0266 | 0.5832 | 0.7235 | |
| Adjusted P-value | 0.0264 † | 0.5077§ | 0.7222† | |
Data represent means ± S.D..
†
Adjusted the effects of age and sex.
§
Adjusted the effects of age, sex and disease duration. 0.025
P<0.05 values are in bold.
b
AS patients with the CC genotype of rs4552569, GG genotype of rs17095830 or heterozygous at both loci were classified into high-risk group and the others were classified into low- risk group.