Table 3:
Death or major cardiovascular event after Escherichia coli O157:H7 gastroenteritis among participants in the Walkerton Health Study with no gastroenteritis (n = 331), mild gastroenteritis (n = 414) or severe gastroenteritis (n = 153)
| Group | No. (%) | No. events per 1000 person-years | Hazard ratio (95% confidence interval) | |
|---|---|---|---|---|
| Unadjusted | Adjusted* | |||
| Death or major cardiovascular event | ||||
| No gastroenteritis | 28 (8.5) | 11.4 | 1.0 (ref) | 1.0 (ref) |
| Mild gastroenteritis | 22 (5.3) | 6.9 | 0.61 (0.35–1.10) | 0.63 (0.36–1.10) |
| Severe | 9 (5.9) | 7.9 | 0.70 (0.33–1.46) | 0.75 (0.35–1.59) |
| Mild or severe gastroenteritis (2 groups combined), n = 567 | 31 (5.5) | 7.2 | 0.63 (0.38–1.05) | 0.66 (0.39–1.10) |
| Major cardiovascular event (death censored) | ||||
| No gastroenteritis | 8 (2.4) | 3.3 | 1.0 (ref) | 1.0 (ref) |
| Mild gastroenteritis | 13 (3.1) | 4.1 | 1.30 (0.52–3.03) | 1.21 (0.50–2.97) |
| Severe gastroenteritis | 6 (3.9) | 5.3 | 1.16 (0.57–4.60) | 1.76 (0.61–5.10) |
| Mild or severe gastroenteritis, n = 567 | 19 (3.4) | 4.4 | 1.35 (0.59–3.08) | 1.35 (0.59–3.12) |
| Death (all causes) | ||||
| None gastroenteritis | 20 (6.0) | 8.0 | 1.0 (ref) | 1.0 (ref) |
| Mild gastroenteritis | 10 (2.4) | 3.1 | 0.39 (0.18–0.83) | 0.41 (0.19–0.89) |
| Severe gastroenteritis | † | † | † | 0.33 (0.10–1.13) |
| Mild or severe gastroenteritis, n = 567 | † | † | † | 0.39 (0.19–0.79) |
*
Adjusted for age, sex, income quintile, diabetes, hypertension, and low sodium diet.
†
Not reported because of count data less than 6. With such low counts, there is a risk of reidentification using Institute for Clinical Evaluative Sciences data. This is under the agreement between the Institute for Clinical Evaluative Sciences and the privacy officer of Ontario.