Table 3.
Reclassification of CHS participants with or without CVD events among three risk groups when changing from standard Model 1 to Model 3, which adds measures of subclinical vascular disease
| Model 3 predicted risk | Total | ||||
|---|---|---|---|---|---|
| <0.30 | 0.30–0.44 | ≥0.45 | |||
| Participants with CVD events | |||||
| Model 1 | <0.30 | 35 | 9 | 5 | 49 |
| predicted | 0.30–0.44 | 21 | 36 | 40 | 97 |
| risk | ≥0.45 | 1 | 21 | 97 | 119 |
| Total | 57 | 66 | 142 | 265 | |
| Participants without CVD events | |||||
| Model 1 | <0.30 | 174 | 22 | 6 | 202 |
| predicted | 0.30–0.44 | 70 | 85 | 40 | 195 |
| risk | ≥0.45 | 5 | 31 | 84 | 120 |
| Total | 249 | 138 | 130 | 517 | |
The NRI values calculated from this table were 0.07 for non-events (p=0.004), 0.04 for events (p=0.26) and 0.12 overall (p=0.01)