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. Author manuscript; available in PMC: 2014 Oct 15.
Published in final edited form as: Adv Drug Deliv Rev. 2012 Aug 17;65(10):1331–1339. doi: 10.1016/j.addr.2012.07.012

Figure 2.

Figure 2

Artwork depicting the LDL particle. The outer shell contains mostly triglyceride and free cholesterol while the internal core contains mostly cholesteryl ester with some triglyceride. The particle is held together by Apo-B100 which wraps around the particle equatorially. SM, sphingomyelin; PC, phosphatidylcholine; TG, triglyceride; CE, cholesteryl ester; UC, unesterified cholesterol. [Reprinted from, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1488, Tiia Hevonoja, Markku O Pentikäinen, Marja T Hyvönen, Petri T Kovanen, Mika Ala-Korpela, Structure of low density lipoprotein (LDL) particles: Basis for understanding molecular changes in modified LDL, 189–210, Copyright (2000), with permission from Elsevier]