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. Author manuscript; available in PMC: 2014 Jan 4.
Published in final edited form as: Circ Res. 2012 Oct 9;112(1):113–127. doi: 10.1161/CIRCRESAHA.112.275586

Figure 6. KLF6 and Sp1 knock down decrease ALK1 expression and inhibit ALK1 upregulation during wound healing.

Figure 6

A. ALK1 levels on HUVEC surface 72h after transfection with siRNA Scrambled or siRNA specific for Sp1, KLF6 or both, at different time points of endothelial denudation in vitro, measured by flow cytometry. Right, representation of fold change in fluorescence intensity by bar histograms. B. Wound healing experiments in HUVEC cells after Sp1 and KLF6 knock down. C. quantification of the healing by measurement of the number of cells migrated to close the wound in each condition.