Figure 2.
Three-dimensional plots for leptin as a function of BMI and four alternative obstructive sleep apnea (OSA) severity measures: a) apnea-hypopnea index (AHI); b) oxygen desaturation index (ODI); c) Hypoxia time (minutes with SaO2 < 90%); and d) minimum SaO2. The significance of associations between leptin levels and sleep apnea severity, obesity and their interaction are shown below the figures. A significant association of obesity and leptin levels is found but no association of OSA and leptin levels and no interaction of OSA and obesity. All plots are adjusted for gender.