Skip to main content
. Author manuscript; available in PMC: 2013 Jan 5.
Published in final edited form as: J Org Chem. 2007 Feb 6;72(5):1675–1680. doi: 10.1021/jo062276g

Scheme 2. Solid-Phase Synthesis of Compounds 2 and 4a.

Scheme 2

a Reagents and conditions: (a) piperidine; (b) Fmoc/t-Bu solid-phase synthesis (ref 15); (c) N-protected linker, HCTU, i-Pr2EtN, DMF; (d) THF/MeOH/N2H4 (70/15/15); (e) pyridine/Ac2O (90/10); (f) TFA/HSCH2CH2SH/PhSMe/H2O (91/3/3/3).