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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2012 Sep 28;88(1):127–129. doi: 10.1016/j.plefa.2012.08.008

Figure 1. Endogenous NPD1 biosynthesis is enhanced upon expression of Ataxin-1 82Q in RPE cells.

Figure 1

Primary human RPE cells were transfected with 82Q. Cells (black bars), NPD1 content in media (white bars) and total (grey bars) was measured by LC MSMS with or without the addition of DHA. * p<0.005. (Figure modified and published with permission from Journal of Biological Chemistry (2012) 287(28):23726-39 “Ataxin 1 Poly(Q)-induced Proteotoxic Stress and Apoptosis are Attenuated in Neural Cells by Docosahexaenoic Acid-derived Neuroprotectin D1”; Calandria JM, et al.)