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. 2012 Dec 17;110(1):276–281. doi: 10.1073/pnas.1214682110

Fig. 1.

Fig. 1.

YY1 binding to Th2 cytokine locus and its expression. (A) YY1 binding to the Th2 cytokine locus in a Th2-specific manner. YY1 binding to regulatory regions at the Th2 cytokine locus in Th1 and Th2 cells was measured by ChIP using an anti-YY1 antibody or control IgG. Data are shown as percentages of input DNA. Error bar shows SD (n = 3). Data are representative of two independent experiments with similar results. (B and C) Th2-specific expression of YY1. Expression of YY1 was measured by quantitative RT-PCR at various time points after stimulation (B) or by immunoblotting at day 4 (C) in Th1 and Th2 cells. Error bar shows SD (n = 3). Statistical difference between YY1 Th1 and YY1 Th2 or between YY1 Th2 and control Th2 was analyzed by Student t test. *P < 0.05.