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. 2012 Dec 18;110(1):111–116. doi: 10.1073/pnas.1201658110

Fig. 3.

Fig. 3.

Binding of C2 domains to lipid vesicles contributes to Rasal RasGAP activity. (A) RasGAP activity of Rasal WT, (DD) and (DDDD) (2.5 µM) colocalized in PC:DOGS-NTA:PS:PI3P 52.5:30:10:7.5 vesicles with 100 µM Ras-GTP. To compare, RasGAP activity of Rasal in the absence of lipids is also shown.