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. 2012 Sep 25;21(1):42–48. doi: 10.1038/mt.2012.203

Figure 3.

Figure 3

Bone marrow analyses of 12-week-old ATM−/− and ATM−/− mCAT+ mice. (a) FACS analyses of total bone marrow cells from femurs of the same mice analyzed in a, followed by (b) total number of hematopoietic stem cells (HSC, Lin− cKit+ Sca-1+), (c) granulocytes-monocytes (Gr-1+ Mac-1+), erythroid cells (Ter119+ CD71+), and lymphoid cells (B220+). (d) Total macrophages obtained upon differentiation in vitro of bone marrow cells from ATM+/+ (n = 4), ATM+/+ mCAT+ (n = 4), ATM−/− (n = 4), and ATM−/− mCAT+ (n = 4) mice. Statistical significance is denoted by *(<0.05), **(<0.005), ***(<0.0005) or ns (not significant). FACS, fluorescence-activated cell sorting.