Pain. (A) Skeletal pain experienced by bone marrow (BM) and peripheral blood stem cell (PBSC) donors at baseline, during the pericollection period, and after donation. (Skeletal pain represents pain in at least 1 of the following sites: back, bone, headache, hip, limb, joint, and neck.) The severity of skeletal pain is defined as the maximum grade among these pain sites. Day 2 is the second day of filgrastim; day 5 is the first day of apheresis. (B) Sites of pain among BM and PBSC donors on the day noted to have the highest severity of pain (1-2 days post-BM collection and day + 5 from start of G-CSF for PBSC).