TABLE 3.

Hazard Ratios for All-Cause and Cardiovascular Disease Mortality According to Body Mass Index and Stratified by Age or Follow-up Time^a

	No. of patients	No. of deaths		HR (95% CI)b
		All-cause	CVD	All-cause mortality	CVD mortality
Age <55 y	7389	326	145
18.5-24.9	2517	111	33	1.00 (reference)	1.00 (reference)
25.0-29.9	3560	157	78	0.91 (0.70-1.17)	1.36 (0.89-2.08)
30.0-34.9	1044	41	23	0.77 (0.52-1.15)	1.16 (0.65-2.09)
≥35	268	17	11	1.61 (0.90-2.88)	2.78 (1.25-6.16)
Age ≥55 y	2174	407	203
18.5-24.9	769	192	98	1.00 (reference)	1.00 (reference)
25.0-29.9	1088	157	81	0.61 (0.49-0.77)	0.58 (0.42-0.80)
30.0-34.9	273	50	19	0.87 (0.63-1.22)	0.59 (0.35-0.99)
≥35	44	8	5	1.33 (0.63-2.80)	1.54 (0.59-4.04)
Follow-up <10 y	3353	287	142
18.5-24.9	848	118	52	1.00 (reference)	1.00 (reference)
25.0-29.9	1710	127	71	0.99 (0.75-1.31)	1.24 (0.83-1.86)
30.0-34.9	611	30	13	1.07 (0.68-1.67)	1.04 (0.53-2.04)
≥35	184	12	6	2.33 (1.19-4.59)	2.38 (0.90-6.26)
Follow-up ≥10 y	6210	446	206
18.5-24.9	2438	185	79	1.00 (reference)	1.00 (reference)
25.0-29.9	2938	187	88	0.72 (0.58-0.89)	0.72 (0.52-1.00)
30.0-34.9	706	61	29	0.96 (0.70-1.32)	0.91 (0.57-1.44)
≥35	128	13	10	1.58 (0.87-2.88)	2.59 (1.25-5.37)

^aCI = confidence interval; CVD = cardiovascular disease; HR = hazard ratio.

^bMultivariable analysis adjusted for age, baseline examination year, physical activity (active or inactive), smoking (current smoker or not), alcohol intake (>14 drinks/wk or not), hypercholesterolemia, hypertension and diabetes (present or not for each), family history of CVD, and cardiorespiratory fitness (treadmill test duration).