TABLE 1.
Related to coronary heart disease risk factors |
Increases serum high-density lipoprotein cholesterol levels |
Reduces serum triglyceride and possibly low-density lipoprotein cholesterol levels |
Reduces indices of obesity |
Reduces arterial blood pressure |
Improves insulin sensitivity and glucose levels |
Improves endothelial function |
Helps with smoking cessation efforts |
Reduces psychological stress |
Hematologic |
Decreases hematocrit and blood viscosity |
Expands blood plasma volume |
Increases red blood cell deformability and tissue-level perfusion |
Increases circulatory fibrinolytic activity |
Other |
Increases coronary flow reserve |
Increases coronary collateral circulation |
Increases tolerance of ischemia |
Increases myocardial capillary density |
Increases ventricular fibrillation thresholds |
Reduces atherosclerosis |
Possibly increases epicardial coronary artery size |
Reduces major morbidity and mortality |
From Mayo Clin Proc.4