Table 2.
Clinicopathological characteristics
| Variable |
PDAC |
uMAC |
SRC |
P-value |
|---|---|---|---|---|
| n= 1002 | n= 54 | n= 320 | ||
| Age, years (mean ± SD) |
54.6 ± 12.8 |
57.3 ± 12.1 |
52.4 ± 12.0 |
0.003 |
| Gender, n (%) |
|
|
|
|
| Male |
605 (60.4) |
35 (64.8) |
187 (58.4) |
0.637 |
| Female |
397 (39.6) |
19 (35.2) |
133 (41.6) |
|
| Multiplicity, n (%) |
|
|
|
|
| Single |
982 (98.0) |
53 (98.1) |
316 (98.8) |
0.612 |
| Multiple |
20 (2.0) |
1 (1.9) |
4 (1.3) |
|
| Tumor location, n (%) |
|
|
|
|
| Upper |
108 (10.8) |
4 (7.4) |
22 (6.9) |
0.184 |
| Middle |
392 (39.1) |
17 (31.5) |
141 (44.1) |
|
| Lower |
452 (45.1) |
31 (57.4) |
139 (43.4) |
|
| Whole |
50 (5.0) |
2 (3.7 %) |
18 (5.6) |
|
| Tumor size, cm (mean ± SD) |
5.7 ± 3.7 |
7.1 ± 3.8 |
4.8 ± 3.2 |
<0.001 |
| Lauren, n (%) |
|
|
|
|
| Intestinal type |
0 (0) |
0 (0) |
0 (0) |
<0.001 |
| Diffuse type |
782 (78.0) |
37 (68.5) |
290 (90.6) |
|
| Mixed type |
220 (22.0) |
17 (31.5) |
30 (9.4) |
|
| Lymphatic invasion, n (%) |
|
|
|
|
| Present |
607 (60.6) |
42 (77.8) |
120 (37.5) |
<0.001 |
| Absent |
395 (39.4) |
12 (22.2) |
200 (62.5) |
|
| Vascular invasion, n (%) |
|
|
|
|
| Present |
105 (10.5) |
12 (22.2) |
27 (8.4) |
0.009 |
| Absent |
897 (89.5) |
42 (77.8) |
293 (91.6) |
|
| Perineural invasion, n (%) |
|
|
|
|
| Present |
490 (48.9) |
29 (53.7) |
108 (33.8) |
<0.001 |
| Absent |
512 (51.1) |
25 (46.3) |
212 (66.3) |
|
| Depth of invasion, n (%) |
|
|
|
|
| T1 |
248 (24.8) |
3 (5.6) |
164 (51.3) |
<0.001 |
| T2 |
152 (15.2) |
4 (7.4) |
32 (10.0) |
|
| T3 |
242 (24.2) |
13 (24.1) |
40 (12.5) |
|
| T4 |
360 (35.9) |
34 (63.0) |
84 (26.3) |
|
| Lymph node metastasis, n (%) |
|
|
|
|
| N0 |
422 (42.1) |
9 (16.7) |
201 (62.8) |
<0.001 |
| N1 |
134 (13.4) |
11 (20.4) |
25 (7.8) |
|
| N2 |
131 (13.1) |
10 (18.5) |
27 (8.4) |
|
| N3 |
315 (31.4) |
24 (44.4) |
67 (20.9) |
|
| Pathological stage, n (%) |
|
|
|
|
| I |
323 (32.2) |
4 (7.4) |
180 (56.3) |
<0.001 |
| II |
212 (21.2) |
11 (20.4) |
50 (15.6) |
|
| III |
354 (35.3) |
30 (55.6) |
64 (20.2) |
|
| IV | 113 (11.3) | 9 (16.7) | 26 (8.1) |