Table 4.
Multivariate analysis of prognostic factors for survival in all enrolled patients
| Variable | Coefficient | SE | Hazard ratio (95% CI) | P-value |
|---|---|---|---|---|
| Age, years |
|
|
|
|
| ≥65/<65 |
0.546 |
0.093 |
1.727 (1.440 to 2.072) |
<0.001 |
| Gender |
|
|
|
|
| Male/Female |
0.229 |
0.088 |
1.257 (1.057 to 1.495) |
0.010 |
| Tumor size, cm |
|
|
|
|
| ≥5/<5 |
0.152 |
0.111 |
1.164 (0.936 to 1.447) |
0.171 |
| Depth of invasion |
|
|
|
|
| T2/T1 |
0.618 |
0.204 |
1.856 (1.245 to 2.766) |
0.002 |
| T3/T1 |
0.856 |
0.188 |
2.353 (1.626 to 3.403) |
<0.001 |
| T4/T1 |
1.532 |
0.184 |
4.629 (3.227 to 6.641) |
<0.001 |
| Lymph node metastasis |
|
|
|
|
| N1/N0 |
0.077 |
0.175 |
1.080 (0.766 to 1.523) |
0.661 |
| N2/N0 |
0.614 |
0.158 |
1.847 (1.356 to 2.516) |
<0.001 |
| N3/N0 |
1.100 |
0.136 |
3.005 (2.301 to 3.925) |
<0.001 |
| Curability |
|
|
|
|
| Non-curative/Curative |
1.104 |
0.110 |
3.016 (2.433 to 3.740) |
<0.001 |
| Histology |
|
|
|
|
| PDAC/SRC |
0.071 |
0.114 |
1.074 (0.858 to 1.343) |
0.534 |
| uMAC/SRC | −0.018 | 0.205 | 0.982 (0.658 to 1.467) | 0.930 |