Table 5.

Virtual screening performance of support vector machines for identifying Src inhibitors from large compound libraries

Inhibitors in training set	Number of inhibitors	1703
	Number of chemical families covered by inhibitors	493
Inhibitors in Testing Set	Number of Inhibitors	44
	Number of Chemical Families Covered by Inhibitors	35
	Percent of Inhibitors in Chemical Families Covered by Inhibitors in Training Set	51.43%
Virtual Screening Performance	Yield	70.45%
	Number and Percent of Identified True Inhibitors Outside Training Chemical Families	15 (34.1%)
	Number and Percent of 13.56M PubChemCompounds Identified as Inhibitors	44,843 (0.33%)
	Number and Percent of the 168K MDDR Compounds Identified as Inhibitors	1,496 (0.89%)
	Number and Percent of the 9,305 MDDR Compounds Similar to the Known Inhibitors Identified as Inhibitors	719 (7.73%)