Table 3.
Comparison of blood pressure, renal function, serum albumin, and urine sodium and potassium after treatment with furosemide alone or with the combination of furosemide plus albumin in chronic kidney disease patients
|
Furosemide |
Furosemide + Albumin |
P-value |
|
|---|---|---|---|
| Mean ± SD | Mean ± SD | ||
| Blood pressure (mmHg) |
|
|
|
| 6 hours systolic |
132.0 ± 5.1 |
132.4 ± 6.2 |
0.60 |
| diastolic |
80.1 ± 5.3 |
80.6 ± 5.3 |
0.52 |
| 24 hours systolic |
131.6 ±4.6 |
132.0 ±5.6 |
0.60 |
| diastolic |
79.7 ± 5.3 |
80.2 ± 5.5 |
0.57 |
| Calculated GFR (mL/min/1.732) |
|
|
|
| 6 hours |
27.8 ± 12.6 |
27.2 ± 10.5 |
0.64 |
| 24 hours |
29.1 ± 12.3 |
28.3 ± 11.3 |
0.23 |
| Serum albumin (g/dL) |
|
|
|
| 6 hours |
2.98 ± 0.30 |
3.46 ± 0.42 |
< 0.01 |
| 24 hours |
2.97 ± 0.31 |
3.42 ± 0.41 |
< 0.01 |
| Urine volume at 6 hours (L) |
0.90 ± 0.35 |
1.07 ± 0.34 |
0.02 |
| Urine volume at 24 hours (L) |
2.44 ± 0.74 |
2.47 ± 0.60 |
0.81 |
| Urine sodium at 6 hours (mEq) |
54.9 ± 31.6 |
70.8 ± 31.3 |
< 0.01 |
| Urine sodium at 24 hours (mEq) |
146.8 ± 59.9 |
154.4 ± 42.2 |
0.53 |
| Urine potassium at 6 hours (mEq) |
14.7 ± 8.0 |
18.0 ± 8.9 |
0.03 |
| Urine potassium at 24 hours (mEq) | 40.5 ± 10.0 | 40.3 ± 7.4 | 0.95 |
GFR = Glomerular filtration rate SD = standard deviation.