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. 2013 Jan 7;8(1):e53522. doi: 10.1371/journal.pone.0053522

Table 1. Enriched pathways in T2D interactome.

Term Corrected p value*
Pathways in cancer 4.52E-27
Prostate cancer 2.02E-17
Chronic myeloid leukemia 4.90E-17
B cell receptor signaling pathway 3.44E-15
Pancreatic cancer 1.38E-13
Glioma 3.24E-13
Focal adhesion 1.19E-12
Proteasome 3.38E-12
Acute myeloid leukemia 3.15E-12
Neurotrophin signaling pathway 1.39E-11
Insulin signaling pathway 2.57E-11
Small cell lung cancer 2.98E-11
T cell receptor signaling pathway 3.35E-10
ErbB signaling pathway 4.29E-10
Non-small cell lung cancer 4.09E-10
Colorectal cancer 7.45E-09
Cell cycle 9.14E-09
Fc epsilon RI signaling pathway 9.32E-09
Type II diabetes mellitus 2.00E-08
Adherens junction 4.16E-08
Melanoma 3.49E-07
Fc gamma R-mediated phagocytosis 3.46E-07
Adipocytokine signaling pathway 7.42E-07
Renal cell carcinoma 1.42E-06
Bladder cancer 1.72E-06
Jak-STAT signaling pathway 2.82E-06
Chemokine signaling pathway 3.28E-06
Endometrial cancer 3.65E-06
Notch signaling pathway 6.27E-06
TGF-beta signaling pathway 6.48E-06
Natural killer cell mediated cytotoxicity 6.30E-06
Aldosterone-regulated sodium reabsorption 7.51E-06
Thyroid cancer 1.01E-05
VEGF signaling pathway 1.44E-05
Progesterone-mediated oocyte maturation 8.87E-05
mTOR signaling pathway 9.80E-05
Leukocyte transendothelial migration 1.25E-04
Oocyte meiosis 1.57E-04
Pathogenic Escherichia coli infection 2.39E-04
Ubiquitin mediated proteolysis 3.04E-04
p53 signaling pathway 3.29E-04
Wnt signaling pathway 3.97E-04
NOD-like receptor signaling pathway 5.10E-04
MAPK signaling pathway 8.07E-04
Regulation of actin cytoskeleton 0.001
Toll-like receptor signaling pathway 0.002
Apoptosis 0.003
Epithelial cell signaling in Helicobacter pylori infection 0.004
Gap junction 0.01
RIG-I-like receptor signaling pathway 0.02
Tight junction 0.02
GnRH signaling pathway 0.02
Long-term depression 0.04
*

Bejamini-Hochberg correction.