Table 7. TGF-beta signaling genes in T2D genome, interactome and transcriptome, and antidiabetic drug toxicogenome.
Genome | Interactome | Transcriptome | Toxicogenome |
CDKN2B | PPP2R1B | CDKN2B | BMP4 |
PPP2R1A | CREBBP | DCN | |
SMAD9 | EP300 | ID2 | |
ROCK1 | MAPK1 | IFNG | |
SMAD5 | MAPK3 | MAPK1 | |
CREBBP | MYC | MAPK3 | |
SMAD4 | PPP2CA | MYC | |
SMAD3 | PPP2R1A | RPS6KB1 | |
RPS6KB2 | PPP2R1B | SP1 | |
RPS6KB1 | ROCK1 | TGFB1 | |
SMAD1 | RPS6KB1 | THBS1 | |
MAPK1 | RPS6KB2 | THBS2 | |
EP300 | SMAD3 | THBS3 | |
CDKN2B | SMAD5 | TNF | |
SP1 | SP1 | ||
PPP2CA | |||
MAPK3 | |||
SMURF1 | |||
MYC |