Table 1.
Baseline characteristics for cases with incident type 2 diabetes mellitus and referents
|
Total population |
|||||
|---|---|---|---|---|---|
| n | Cases | n | Referents | p-value | |
| Time to T2DM diagnosis, years |
157 |
5.5 ± 2.7 |
- |
- |
- |
| Age, years |
157 |
50.5 ± 8.1 |
277 |
50.2 ± 8.3 |
matched |
| Sex, male (%) |
157 |
56.7 |
277 |
56.7 |
matched |
| Family history of T2DM, n (%) |
154 |
48 (31.4) |
269 |
44 (16.4) |
< 0.001 |
| Non, Ex, Daily smoking, n (%) |
156 |
56 (35.9), 56 (35.9), 44 (28.2) |
272 |
112 (41.2) 105 (38.6) 55 (20.2) |
0.163 |
| Sedentary, Moderate, Active, n (%) |
157 |
23 (14.6), 116 (73.9), 18 (11.5) |
277 |
48 (17.3), 190 (68.6), 39 (14.1) |
0.507 |
| Hypertension*, n (%) |
157 |
104 (66.2) |
277 |
39 (32.1) |
< 0.001 |
| Antihypertensive medication, n (%) |
157 |
41 (26.1) |
277 |
16 (5.8) |
< 0.001 |
| Systolic blood pressure, mmHg |
157 |
139.2 ± 18.3 |
276 |
127.5 ± 16.8 |
< 0.001 |
| Diastolic blood pressure, mmHg |
157 |
87.0 ± 12.5 |
276 |
79.7 ± 10.4 |
< 0.001 |
| Fasting plasma glucose, mmol/L |
157 |
5.9 ± 0.8 |
277 |
5.2 ± 0.7 |
< 0.001 |
| 2-h plasma glucose, mmol/L |
157 |
8.2 ± 2.1 |
277 |
6.5 ± 1.7 |
< 0.001 |
| BMI, kg/m2 |
156 |
29.5 ± 4.2 |
277 |
25.3 ± 3.6 |
< 0.001 |
| Total cholesterol, mmol/L |
157 |
6.0 ± 1.0 |
277 |
5.7 ± 1.0 |
< 0.001 |
| HDL, mmol/L |
157 |
1.1 ± 0.3 |
277 |
1.3 ± 0.3 |
0.002 |
| Triglycerides, mmol/L |
157 |
1.7 (1.3 - 2.5) |
277 |
1.1 (0.9 - 1.6) |
< 0.001 |
| tPA, ng/mL |
156 |
11.0 (8.7 - 13.7) |
276 |
7.7 (5.6 - 10.5) |
< 0.001 |
| PAI-1, ng/mL |
157 |
35.0 (23.9 - 46.1) |
276 |
21.2 (14.6 - 31.3) |
< 0.001 |
| tPA/PAI-1 complex, ng/mL |
155 |
7.9 (5.2 - 0.4) |
277 |
3.8 (2.5 - 5.8) |
< 0.001 |
| VWF, % | 156 | 142.9 (119.1 - 178.9) | 276 | 124.0 (96.0 - 159.6) | < 0.001 |
Values are mean ± SD for continuous, and percent for non-continuous variables. Median and interquartile range presented for variables not displaying normal distribution.
BMI: body mass index; CRP: C-reative protein; T2DM: type 2 diabetes mellitus; tPA: tissue plasminogen activator; PAI-1: plasminogen activator inhibitor-1; VWF: von Willebrand factor; SD: standard deviation.