Table 2.
Risk of incident type 2 diabetes in 157 cases compared to 277 referents
| OR | 95% CI | p-value | |
|---|---|---|---|
| Family history of T2DM |
2.46 |
1.52 - 3.97 |
< 0.001 |
| Smoking (daily vs non-smoker) |
1.69 |
0.98 - 2.89 |
0.059 |
| Physical activity (sedentary vs active) |
0.94 |
0.44 - 2.02 |
0.878 |
| Hypertension* |
3.85 |
2.48 - 5.97 |
< 0.001 |
| Systolic blood pressure |
2.00 |
1.58 - 2.54 |
< 0.001 |
| Diastolic blood pressure |
1.93 |
1.51 - 2.47 |
< 0.001 |
| Fasting plasma glucose |
3.77 |
2.68 - 5.32 |
< 0.001 |
| 2-h plasma glucose |
2.65 |
2.03 - 3.47 |
< 0.001 |
| BMI |
3.09 |
2.29 - 4.18 |
< 0.001 |
| Triglycerides |
2.38 |
1.84 - 3.07 |
< 0.001 |
| CRP |
1.91 |
1.51 - 2.42 |
< 0.001 |
| tPA |
2.63 |
1.96 - 3.54 |
< 0.001 |
| PAI-1 |
2.33 |
1.79 - 3.03 |
< 0.001 |
| tPA/PAI-1 complex |
4.02 |
2.84 - 5.69 |
< 0.001 |
| VWF | 1.73 | 1.36 - 2.19 | < 0.001 |
* Blood pressure ≥ 140/90 and/or on antihypertensive medication.
Conditional logistic regression analysis. OR and 95% CI, per 1 SD increment.
Referents were matched for age and sex. Natural logarithm transformation was used for haemostatic markers, C-reactive protein and triglycerides.
OR: odds ratio; CI: confidence interval; SD: standard deviation; BMI: body mass index; CRP: C-reactive protein; T2DM: type 2 diabetes mellitus; tPA: tissue plasminogen activator; PAI-1: plasminogen activator inhibitor-1; VWF: vn Willebrand factor.