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. 2013 Jan 7;8(1):e53015. doi: 10.1371/journal.pone.0053015

Table 3. Antigens downregulated in metastasis.

Antigen Cell line (% Positivity)
SW480 SW620 SW480/SW620 ratio
EGFR 51.50 1.12 −45.98
CD21 22.84 0.51 −44.78
CD56/NCAM 49.48 1.17 −42.29
CD184/CXCR4 17.55 0.62 −28.31
CD73 22.64 0.88 −25.73
CD120b 35.33 1.65 −21.41
CD57 94.71 5.10 −18.57
CD162/SELPLG 8.49 0.51 −16.65
CD7 6.31 0.51 −12.37
CD70 * 7.19 0.59 −12.19
CD87/uPAR 7.33 0.63 −11.63
CD3 * 5.79 0.70 −8.27
CD95/FASR 62.95 7.84 −8.03
CD8b * 6.55 0.82 −7.98
CD33 * 5.76 0.77 −7.48
CDw93 * 5.14 0.72 −7.14
CD209/DC-SIGN 10.76 2.16 −4.98
CD45RA * 5.83 1.22 −4.78
CD91/LRP-1 13.88 2.94 −4.72
CD79b * 7.32 1.62 −4.52
CD153 * 11.70 2.65 −4.42
CD130/gp130 9.15 2.16 −4.24
CD337/NCR3 * 7.32 1.74 −4.21
CD100/SEMA4D 6.60 1.58 −4.18
CD193/CCR3 * 8.01 1.97 −4.07
CD271/LNGFR 76.08 19.47 −3.91
CD181/IL8RA * 5.07 1.31 −3.87
CD6 * 8.09 2.10 −3.85
CD243/P-gp * 52.5 13.82 −3.80
CD61/Integrin β3 * 5.22 1.51 −3.46
CD75 * 8.54 2.55 −3.35
CD107b * 7.61 2.32 −3.28
CD108 7.16 3.22 −2.22
CD54/ICAM1 57.18 27.45 −2.08
CD55 73.75 36.77 −2.01

Antibody array results showing surface antigens that were at least two-fold decreased in cell positivity in SW620 (metastatic) as compared to SW480 (primary). Abbreviations: epidermal growth factor receptor, EGFR; neural cell adhesion molecule, NCAM; C-X-C chemokine receptor 4, CXCR4; selectin P ligand, SELPLG; urokinase receptor, UPAR; FAS receptor, FasR; dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin, DC-SIGN; low density lipoprotein receptor related protein 1, LRP1; glycoprotein 130, gp130; natural cytotoxicity triggering receptor 3, NCR3; semaphorin-4D, SEMA4D; C-C chemokine receptor 3, CCR3; low affinity nerve growth factor receptor; LNGFR; interleukin 8 receptor alpha, IL8RA; P-glycoprotein, P-gp; intercellular adhesion molecule 1, ICAM1.

*

, Antigen was not two-fold decreased by comparison of mean fluorescence intensities (Table S4).