Table 1. Summary of DSM-IV based, life-time diagnoses of substance addictions in study participants.
Number of Individuals | ||
European Americans | African Americans | |
Cocaine Dependence | ||
Cases | 1014 | 1178 |
controls | 418 | 335 |
Co-morbid ND in cases | 786 (77.51%) | 762 (64.68%) |
Co-morbid ND in controls | None | None |
Co-morbid AD in cases | 639 (63.02%) | 657 (55.77%) |
Co-morbid AD in controls | 59 (14.11%) | 55 (16.42%) |
Co-morbid OD in cases | 697 (68.74%) | 312 (26.48%) |
Co-morbid OD in controls | 34 (8.13%) | 19 (5.67%) |
Co-morbid MDD in cases | 208 (20.51%) | 162 (13.75%) |
Co-morbid MDD in controls | 36 (8.61%) | 29 (8.66%) |
Nicotine Dependence | ||
Cases | 1029 | 845 |
controls | 418 | 335 |
Co-morbid CD in cases | 786 (76.38%) | 762 (90.28%) |
Co-morbid CD in controls | None | None |
Co-morbid AD in cases | 630 (61.22%) | 510 (60.35%) |
Co-morbid AD in controls | 59 (14.11%) | 247 (73.73%) |
Co-morbid OD in cases | 718 (69.78%) | 260 (30.77%) |
Co-morbid OD in controls | 34 (8.13%) | 103 (30.75%) |
Co-morbid MDD in cases | 213 (20.70%) | 130 (15.38%) |
Co-morbid MDD in controls | 36 (8.61%) | 72 (21.49%) |
Cocaine-Induced Paranoia | ||
CD cases without CIP | 328 | 364 |
CD cases with CIP | 686 | 814 |
controls | 418 | 335 |
Co-morbid ND in cases without CIP | 242 (73.78%) | 226 (62.09%) |
Co-morbid ND in cases with CIP | 544 (79.30%) | 536 (65.85%) |
Co-morbid ND in controls | None | None |
Co-morbid AD in cases without CIP | 186 (56.71%) | 173 (47.53%) |
Co-morbid AD in cases with CIP | 453 (66.03%) | 484 (59.46%) |
Co-morbid AD in controls | 59 (14.11%) | 55 (16.42%) |
Co-morbid OD in cases without CIP | 228 (69.51%) | 98 (26.92%) |
Co-morbid OD in cases with CIP | 469 (68.37%) | 214 (26.29%) |
Co-morbid OD in controls | 34 (8.13%) | 19 (5.67%) |
Co-morbid MDD in cases without CIP | 61 (18.60%) | 49 (13.46%) |
Co-morbid MDD in cases with CIP | 147 (21.43%) | 113 (13.88%) |
Co-morbid MDD in controls | 36 (8.61%) | 29 (8.66%) |
CD = cocaine dependence, ND = nicotine dependence, AD = alcohol dependence, OD = opiate dependence, MDD = major depression disorder, CIP = cocaine induced paranoia.