Skip to main content
. 2013 Jan 7;8(1):e49368. doi: 10.1371/journal.pone.0049368

Table 1. Summary of DSM-IV based, life-time diagnoses of substance addictions in study participants.

Number of Individuals
European Americans African Americans
Cocaine Dependence
Cases 1014 1178
controls 418 335
Co-morbid ND in cases 786 (77.51%) 762 (64.68%)
Co-morbid ND in controls None None
Co-morbid AD in cases 639 (63.02%) 657 (55.77%)
Co-morbid AD in controls 59 (14.11%) 55 (16.42%)
Co-morbid OD in cases 697 (68.74%) 312 (26.48%)
Co-morbid OD in controls 34 (8.13%) 19 (5.67%)
Co-morbid MDD in cases 208 (20.51%) 162 (13.75%)
Co-morbid MDD in controls 36 (8.61%) 29 (8.66%)
Nicotine Dependence
Cases 1029 845
controls 418 335
Co-morbid CD in cases 786 (76.38%) 762 (90.28%)
Co-morbid CD in controls None None
Co-morbid AD in cases 630 (61.22%) 510 (60.35%)
Co-morbid AD in controls 59 (14.11%) 247 (73.73%)
Co-morbid OD in cases 718 (69.78%) 260 (30.77%)
Co-morbid OD in controls 34 (8.13%) 103 (30.75%)
Co-morbid MDD in cases 213 (20.70%) 130 (15.38%)
Co-morbid MDD in controls 36 (8.61%) 72 (21.49%)
Cocaine-Induced Paranoia
CD cases without CIP 328 364
CD cases with CIP 686 814
controls 418 335
Co-morbid ND in cases without CIP 242 (73.78%) 226 (62.09%)
Co-morbid ND in cases with CIP 544 (79.30%) 536 (65.85%)
Co-morbid ND in controls None None
Co-morbid AD in cases without CIP 186 (56.71%) 173 (47.53%)
Co-morbid AD in cases with CIP 453 (66.03%) 484 (59.46%)
Co-morbid AD in controls 59 (14.11%) 55 (16.42%)
Co-morbid OD in cases without CIP 228 (69.51%) 98 (26.92%)
Co-morbid OD in cases with CIP 469 (68.37%) 214 (26.29%)
Co-morbid OD in controls 34 (8.13%) 19 (5.67%)
Co-morbid MDD in cases without CIP 61 (18.60%) 49 (13.46%)
Co-morbid MDD in cases with CIP 147 (21.43%) 113 (13.88%)
Co-morbid MDD in controls 36 (8.61%) 29 (8.66%)

CD = cocaine dependence, ND = nicotine dependence, AD = alcohol dependence, OD = opiate dependence, MDD = major depression disorder, CIP = cocaine induced paranoia.