Table 1. Comparison of the missing peak rate of the fixed number-based method () and the Benjamini-Hochberg (B-H) algorithm with on the 32 spectra of the eight proteins in the benchmark dataset as picked by WaVPeak.
Spectra | 15N-HSQC | HNCO | HNCA | HNCACB | CBCA(CO)NH | |||||||||||
Protein | Len | tNp | B-H | (d) | tNp | B-H | (d) | tNp | B-H | (d) | tNp | B-H | (d) | tNp | B-H | (d) |
RP3384 | 64 | 7 | 7 | (0) | 0 | 0 | (0) | 12 | 12 | (0) | – | – | 8 | 8 | (0) | |
CASKIN | 67 | 6 | 2 | (67) | 22 | 15 | (32) | – | – | 38 | 41 | (−8) | 10 | 10 | (0) | |
VRAR | 72 | 3 | 3 | (0) | 7 | 7 | (0) | – | – | 31 | 32 | (−3) | 18 | 18 | (0) | |
HACS1 | 74 | 7 | 2 | (71) | 8 | 6 | (25) | – | – | 14 | 15 | (−7) | 8 | 6 | (25) | |
TM1112 | 89 | 8 | 2 | (75) | – | – | 6 | 6 | (0) | 8 | 7 | (13) | 9 | 2 | (78) | |
COILIN | 98 | 3 | 0 | (100) | 16 | 17 | (−6) | – | – | 24 | 25 | (−4) | 28 | 20 | (29) | |
ATC1776 | 101 | 7 | 5 | (29) | 8 | 7 | (13) | 19 | 17 | (11) | – | – | 25 | 24 | (4) | |
YST0336 | 146 | 2 | 2 | (0) | 6 | 3 | (50) | 11 | 10 | (9) | – | – | 17 | 13 | (24) | |
Average | 5.4 | 2.9 | (43) | 9.6 | 7.9 | (16) | 12 | 11.2 | (5) | 23 | 24 | (−2) | 15.4 | 12.6 | (20) | |
SDave | 2.2 | 2.0 | 6.7 | 5.7 | 4.6 | 3.9 | 10.9 | 12.0 | 7.4 | 7.0 | ||||||
Preave | 84 | 77 | 77 | 73 | 83 | 76 | 64 | 71 | 72 | 67 |
Column is the relative improvement of the missing peak rate of B-H over . All values except the last two rows are the missing peak rates. The “” row lists the standard deviations of the missing peak rates for the corresponding columns, demonstrating the robustness of different methods. The last row is the average precision value. All values are given in percentage.