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. 2013 Jan 7;8(1):e53692. doi: 10.1371/journal.pone.0053692

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© 2013 Hozumi et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) LPS (20 μg/mouse) was administered i.v. to CAR (5 mg/mouse)-primed C57BL/6 mice, and their livers were extirpated after 12 h of LPS injection. (B) LPS (0.5 μg/mouse) was administered i.v. to D-galN (20 mg/mouse)-primed C57BL/6 mice, and their livers were extirpated after 6 h of LPS injection. (C) Untreated mice were used as negative control. Arrow represents apoptotic cells. Magnification: ×200.