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. 2013 Jan 7;8(1):e53648. doi: 10.1371/journal.pone.0053648

Figure 5. mAb 8G9 to LMα5 chain strongly inhibits binding of isolated α3β1 integrin to immobilized laminins 511 and 521.

Figure 5

A) α3β1 integrin binds rhLMs 511 and 521, but not rhLM411. B) Effect of mAbs to LMα5 chain on the binding of α3β1 integrin to rhLM511. C) Effect of mAbs to LMα5 chain on the binding of α3β1 integrin to rhLM521. Statistical analyses (Student's t-test) including mean and SD were calculated, as well as level of significance of integrin binding to rhLMs 411, 511 and 521 when compared to HSA (A), and effect of antibodies when compared to mouse IgG on integrin binding to rhLMs 511 (B) and 521 (C) (*, p<0.05; **, p<0.01; ***, p<0.001).