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. 2013 Jan 7;8(1):e53648. doi: 10.1371/journal.pone.0053648

Figure 6. mAb 4E10 to a LMβ1 chain epitope near the globular domain of laminin-511 hinders the binding of mAb 8G9.

Figure 6

A) mAb 4C7 and other LMα5 antibodies minimally affect the binding of mAb 8G9 to rhLM511. B) mAb 4E10 largely competes with the binding of mAb 8G9 to rhLM511. Statistical analyses (Student's t-test) including mean and SD were calculated, as well as level of significance of the effect of the mAbs on the binding of biotinylated-8G9 to rhLM511 when compared to mouse IgG. Competing antibodies were used at 50x higher concentration than biotinylated-8G9 (*, p<0.05; **, p<0.01; ***, p<0.001).