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. 2012 Dec 13;12:597. doi: 10.1186/1471-2407-12-597

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Copyright ©2012 Serce et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Abundant SERBP1 expression is associated with low PAI-1 protein level in Western blot analysis. SERBP1 protein expression was investigated in extracts of cryoconserved human breast cancer tissues with low (n = 8) and high (n = 8) levels of protein PAI-1 by using Western blot analysis. Extracts with low PAI-1 protein levels (number: 1-3) were associated with intense SERBP1 expression by trend and vice versa high PAI-1 protein levels (number: 4-6) correlated with low SERBP1 expression. Differences between the respective groups were statistically not significant (P = 0.281). β-actin showed a relatively homogenous protein loading in the investigated lysates.