Table 1. Cardiac function measured by echocardiography 13 weeks after TAC or sham surgery.
| Parameter | FVB sham | FVB TAC | Mb sham | Mb TAC |
| BW (g) | 30.4±0.8 | 30.8±0.8 | 29.3±0.7 | 30.6±0.9 |
| LVEDD (mm) | 3.81±0.08 | 4.15±0.05a | 3.97±0.08 | 4.40±0.08a,b |
| LVESD (mm) | 2.36±0.10 | 2.76±0.08a | 2.48±0.07 | 3.17±0.09a,b |
| IVS (D) (mm) | 0.91±0.02 | 1.02±0.03a | 0.86±0.03 | 1.03±0.02a |
| IVS (S) (mm) | 1.18±0.03 | 1.29±0.03a | 1.13±0.02 | 1.25±0.02a |
| PWTh (D)(mm) | 0.80±0.04 | 0.89±0.03a | 0.74±0.02 | 0.88±0.03a |
| PWTh (S)(mm) | 1.16±0.04 | 1.25±0.02a | 1.11±0.04 | 1.25±0.05a |
| IVS%Th | 30.9±2.8 | 29.3±3.5 | 33.6±3.6 | 24.1±2.26 |
| PW%Th | 40.7±5.2 | 40.3±3.8 | 44.7±1.9 | 42.0±4.0 |
| IVS/PW | 1.16±0.05 | 1.13±0.03 | 1.15±0.04 | 1.15±0.05 |
| %FS | 38.6±1.7 | 33.8±1.1a | 37.4±1.3 | 27.1±1.1a,b |
| HR | 487±10 | 516±11 | 533±7 | 525±16 |
Legend: Data are mean±SE.
a
indicates p<0.05 for FVB-sham vs. FVB-TAC and for Mb-sham vs. Mb-TAC;
b
indicates p<0.05 for Mb-TAC vs. FVB-TAC, n = 8 for sham groups, n = 12 for TAC groups. LVEDD, left ventricular end diastolic diameter; LVESD, left ventricular end systolic diameter; IVS(D), interventricular septum thickness at diastole; IVS(S), interventricular septum thickness at systole; PWTh(D), post wall thickness at diastole; PWTh(S), post wall thickness at systole; IVS%Th, interventricular septum % thickening; PW%Th, posterior wall % thickening; IVS/PW, interventricular septum to posterior wall thickness ratio; %FS, percent fractional shortening; HR, heart rate. Data were analyzed by two way ANOVA.