Table 4. Performance comparison among various types of sequence features and methods for the across-germline prediction using 10-fold cross-validation.
Method | Sensitivity | Specificity | Accuracy (%) |
Random Forests (AAC) | 0.846 | 0.742 | 80.09 |
Random Forests (DPC) | 0.862 | 0.823 | 84.49 |
Random Forests (PPs) | 0.837 | 0.704 | 78.01 |
Random Forests (AAC+DPC) | 0.870 | 0.801 | 84.03 |
Random Forests (AAC+PPs) | 0.837 | 0.715 | 78.47 |
Random Forests (DPC+PPs) | 0.862 | 0.780 | 82.64 |
Random Forests (AAC+DPC+PPs) | 0.862 | 0.785 | 82.87 |