Table 5. Performance comparison among various types of sequence features and methods for the novel-germline prediction.
Method | Sensitivity | Specificity | Accuracy (%) |
Random Forests (AAC) | 0.626 | 0.581 | 60.65 |
Random Forests (DPC) | 0.785 | 0.640 | 72.22 |
Random Forests (PPs) | 0.675 | 0.484 | 59.26 |
Random Forests (AAC+DPC) | 0.768 | 0.634 | 71.06 |
Random Forests (AAC+PPs) | 0.671 | 0.522 | 60.65 |
Random Forests (DPC+PPs) | 0.732 | 0.629 | 68.75 |
Random Forests (AAC+DPC+PPs) | 0.699 | 0.602 | 65.74 |
BLAST [44] | 0.411 | 0.645 | 51.16 |