Table 5. Pleural Effusion Status and Variables between Medical Treatment Success and Medical Treatment Failure Patients.

	Medical success	Medical failure
	(n = 54)	(n = 10)	p value
Effusion status
Effusion CXR score, %, mean ± SD	45±13	66±6	<0.001
Multi-loculation, n (%)	12 (22)	10 (100)	<0.001
Pleural fluid
pH value	7.23 (7.15–7.41, n = 53)	7.14 (6.80–7.3, n = 7)	0.16
Glucose, mg/dl	116 (77–157)	51 (27–90)	<0.001
LDH, IU/dl	316 (129–1618)	2219 (1519–3332)	<0.001
Leukocyte count, cells/µl	2080 (460–8230)	10080 (1450–185000)	0.09
PAI-1, ng/ml	104.0 (80.8–198.0)	102.5 (52.6–117.0)	0.46
tPA, ng/ml	11.5 (4.2–17.4)	8.2 (3.2–17.0)	0.16
PAI-1/tPA ratio	13.6 (4.5–26.9)	13.1 (5.5–17.1)	0.10
IL-8, pg/ml	6141 (4845–6349)	6349 (6122–6773)	<0.001
VEGF, pg/ml	3872 (2019–5271)	5503 (5384–5601)	<0.001

See Table 1 for definition of the abbreviations. Data are presented as the median (IQR) unless specified.