Figure 6.
Imaging of tissue vascularization. Panels show the same graft as in Figure 5. Blood vessels were visualized by an intravenous injection of a 70 kDa Texas Red labeled dextran. GFP (a) and Texas Red (b) were excited with a two-photon laser at 890 nm at minimal necessary laser power required and emission collected onto nondescanned detectors using a dichroic mirror (RSP 560) and emission filters (BP 525/50 and BP 640/20). (c) Overlay of a and b. Objective APO 10 × 0.3 W. Pinhole: 1 airy unit. Zoom factor: 1.7. Image bit depth: 8 bit. Resolution xyz: 1.38 × 1.38 ×5 μm. Scale bar: 100 μm.