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Representative images of fibronectin (FN) immunostaining in renal tubular area (stained dark brown). Sham (A) and streptozotocin-induced diabetic rats treated with vehicle (B), amlodipine (C) or aliskiren (D) individually and combined (E). FN immunostaining was increased in vehicle treated diabetic rats, reduced with aliskiren alone or combined with amlodipine and not affected by amlodipine alone treatment. x200 magnification.
