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. Author manuscript; available in PMC: 2014 Jan 15.
Published in final edited form as: J Immunol. 2012 Dec 19;190(2):650–658. doi: 10.4049/jimmunol.1102486

FIGURE 5. Microarray analysis of gene induction following infection by DCV, FHV or SINV.

FIGURE 5

(A) Venn diagram showing the number of upregulated genes (by a factor of at least 2) following infection by the three viruses. The total number of genes regulated by each virus is indicated in parenthesis. (B) FHV and SINV induce members of the same gene families, but FHV triggers a stronger response. The number of genes belonging to seven gene ontology (GO) functional categories induced by both FHV and SINV or by FHV only are shown. (C) Expression of vir-1 and TotM by Q-PCR normalized for the expression of the housekeeping gene RpL32. Groups of 10 wild-type (OR) flies were injected with Tris buffer or the viruses DCV, CrPV, FHV, SINV, VSV, DXV, IIV6 or pricked with a needle dipped in a concentrated pellet of the Gram-positive bacteria M. luteus and the Gram-negative bacteria E. coli. RNA was extracted at 6h, 1d, 2d, 3d and 4d after challenge. The data represent the mean and the standard errors of at least two independent experiments. p-values were calculated for each time point individually versus the Tris injected control. *p<0.05, **p<0.01, ***p<0.001.