Table 2.
Dose (mg/kg) | Tmaxa (min) | Cmaxb (ng/mL) | T1/2c (min) | AUClastd (min*ng/mL) | AUCINFe (min*ng/mL) |
---|---|---|---|---|---|
5 | 60 | 263.7 ± 38.6 | 70.0 ± 1.3 | 32860 ± 9230 | 33000 ± 9280 |
10 | 60 | 548.9 ± 199.4 | 53.8 ± 0.8 | 79290 ± 34230 | 79430 ± 34300 |
Tmax = time required to reach maximum concentration
Cmax = maximum concentration
T1/2 = half-life
AUClast = area under the curve from time zero to last quantifiable concentration
AUCINF = area under the curve from zero to infinite time