Table 1. Characteristics of study participants.
| Controls (n=13) | Patients (n=12) | P-value C vs P | Excluded controls (n=2) | |
|---|---|---|---|---|
| Males (n) | 10 | 9 | 1* | 2 |
| Age (years) | 70.5 (0.5) | 67.6 (8.6) | 0.27† | 71(0) |
| Current smoker (n) | 0 | 4 | 0.04* | 0 |
| Hypertension (n) | 2 | 10 | 0.001* | 0 |
| Diabetes (n) | 0 | 3 | 0.09* | 0 |
| Previous myocardial infarction (n) | 0 | 3 | 0.09* | 0 |
| Statin treatment (n) | 0 | 9 | <0.001* | 0 |
| Aspirin | 0 | 12 | <0.001* | 0 |
| Cerebrovascular event | <0.001* | |||
| Minor brain infarction (n) | 0 | 5 | 0.01* | 0 |
| Transient ischemic symptoms (n) | 0 | 4 | 0.04* | 0 |
| Retinal artery (n) | 0 | 3 | 0.09* | 0 |
| BMI, kg m−2 | 23.7 (2.9)‡ | 25.8 (2.4)§ | 0.08† | 25.6 (8.8) |
| Cholesterol (mmol l−1) | 5.59 (1.20) | 4.62 (1.59) | 0.10† | 5.38 (0.62) |
| Triglycerides (mmol l−1) | 1.19 (0.74) | 1.72 (1.08) | 0.04|| | 1.8 (0.77) |
| HDL cholesterol (mmol l−1) | 1.67 (0.44) | 1.32 (0.26) | 0.026† | 1.49 (0.63) |
| LDL cholesterol (mmol l−1) | 3.39 (1.05) | 2.53 (1.44) | 0.10† | 3.07 (0.91) |
| ApoA1 | 1.44 (0.20) | 1.33 (0.21) | 0.22† | 1.46 (1.48) |
| ApoB | 1.09 (0.29) | 0.95 (0.34) | 0.27† | 1.16 (0.42) |
| WBC | 5.47 (1.06)§ | 7.78 (1.56)‡ | <0.001† | 5.05 (1.77) |
| hsCRP (mg l−1) | 2.14 (3.35) | 4.81 (5.95) | 0.12|| | 1.81 (2.27) |
BMI, body mass index; hsCRP, high-sensitivity C-reactive protein; LDL, low-density lipoprotein; WBC, white blood cell count.
Data are mean (s.d.) unless otherwise indicated.
*Fisher’s exact test.
†Welch’s t-test.
‡n=11.
§n=10.
||Wilcoxon rank-sum test.