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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Eur J Neurosci. 2012 Oct 29;37(1):1–9. doi: 10.1111/ejn.12037

Figure 2. Cocaine treatment significantly increases overall spine density in βAdd KO and WT mice.

Figure 2

Following repeated cocaine administration (15 mg/kg, , i.p.; 10 days), spine density was measured in the NAc of βAdd KO mice and their WT siblings. Density (spine number/um) of A) Total, B) mushroom, C) thin, and D) stubby spines was measured using NeuronStudio. There was a significant increase in the number of mushroom and thin spines in the NAc of βAdd WT and KO mice following cocaine treatment (*, p ≤ 0.05 post hoc analysis, Tukey's-HSD).