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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Eur J Neurosci. 2012 Oct 29;37(1):1–9. doi: 10.1111/ejn.12037

Figure 3. Mushroom spine density is greatly increased in βAdd KO mice following cocaine treatment.

Figure 3

The percentage change in density of A) total, B) mushroom, C) thin, and D) stubby spines over saline-treatment was measured following repeated cocaine administration (15 mg/kg, , i.p.; 10 days), spine density was measured in the NAc of βAdd KO mice and their WT siblings using NeuronStudio. There was a significant increase in the density of mushroom spines in the NAc of βAdd KO mice following cocaine treatment (*, p ≤ 0.05).