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. 2012 Jul 13;28(1):127–135. doi: 10.1007/s11606-012-2145-y

Table 1.

Summary of Included Studies

Study (year) Study design Country Number of centers Sample size (CCM Intervention/Control) Intervention Measures of performance reported (Effective*/Total (%))
Process Measures Outcome Measures
Bucher (2010) RCT Switzerland 7 Physicians randomized (57/60) CIS– Audit/feedback 0/4
Patients randomized (1634/1632)
Pyne (2011) RCT U.S.A 3 138/138 DS– Communication and case discussion 2/8 (25%)
 Medical: 0/4
 Psych: 2/4 (50.0%)
Landon (2004) CBA U.S.A 44 intervention/25 control clinics 6406/3580 CIS– Presence of quality monitoring 0/6 0/2
 Imm/Vir: 0/1
 Economic: 0/1
Fonquernie (2010) PCS France 1 1717/1717 DS– Explicit mention of implementation of guidelines CIS– Reminders, Change in medical records systems 4/8 (50%) 2/2 (100%)
Medical: 1/1 (100%)
Psych: 1/1 (100%)
Gardner (2008) PCS U.S.A 17 1091/1091 DS– Educational meetings 1/1 (100%) 1/1 (100%)
CIS– Audit/feedback  Medical: 1/1 (100%)
Horswell (2008) PCS U.S.A 8 3708/3708 CIS– Reminders, Change in medical records systems 2/6 (33.3%) 1/4 (25%)
 Imm/vir: 1/2 (50%)
 Medical: 0/1
 Economic: 0/1
Kitahata (2003) PCS U.S.A 1 1204/1204 CIS– Reminders 4/12 (33.3%)
Belperio (2009) RCS U.S.A Not reported 7220/7220 DS– Distribution of educational materials 1/4 (25%)
Brown (2002) RCS U.S.A 1 73/73 CIS– Reminders 5/5 (100%)
Ma (2010) RCS U.S.A 1 75/75 DS– Communication and case discussion 3/4 (75%)
 Imm/Vir: 2/3 (66.7%)
 Medical: 1/1 (100%)
Natha (2008) RCS U.K. 1 100/100 DS– Explicit mention of implementation of guidelines 4/5 (80%)
Shuter (2003) RCS U.S.A 1 1026/1026 CIS– Audit/feedback 1/1 (100%)
Magnus (2009) SCS U.S.A 8 Not reported CIS– Reminders, Change in medical records systems 1/3 (33.3%)
Morris (2009) TS Zambia 19 Not reported DS– Educational meetings 0/3
CIS– Audit/feedback, Presence of quality monitoring
Youngleson (2010) TS South Africa 17 Not reported CIS– Presence of quality monitoring 4/4 (100%)
Were (2010) TM Uganda 1 94/88 CIS– Reminders, Change in medical records systems 2/3 (66.7%)
 Economic: 2/3
Total 27/62 (43.5%) 11/24 (45.8%)
 Imm/Vir: 3/6 (50.0%)
 Medical: 3/8 (37/5%)
 Psych: 3/5 (60.0%)
 Economic: 2/5 (40.0%)

*Effective: Process or outcome measures showing statistically significant improvement

RCT: Randomized Clinical Trial, CCT: Controlled Clinical Trial, PCS or RCS: Prospective or Retrospective Cohort Study, CBA: Controlled before and after design, SCS: Serial Cross-sectional Study, TS: Time series (Interrupted), TM: Time-motion Study (Prospective)

Psych: Psychosocial measures, Imm/Vir: Immunological/Virological measures