Figure 2. Impaired long-term novel Object Recognition.
(A) During training both groups of animals spent approximately equal time exploring both objects (wt: n = 10, 48.57 ± 2.94%; NR2A: n = 10, 50.15 ± 0.93%). During the one hour retention test the tg-NR2A animals and their wild-type littermates spent approximately equal time investigating the novel object (wt: n = 10, 61.46 ± 1.55%; NR2A: n = 10, 57.80 ± 3.53%). (B) In the 24 hour recall session the tg-NR2A showed no preference for the novel object (NR2A: n = 10 49.59 ± 4.00%) whereas the wild-type animals show significantly more interest in the novel object (wt: n = 10, 72.67 ± 5.74). * p = 0.015.