Table 3.

Results of the path analyses based on the Structural Equation Models – the table consist of the standardized betas, standard errors and p-values of the paths analyzed between pairs of variables.

Path	Significant	Standardized Beta	Std. Error	P-value
Paths between the lifestyle variables and imaging biomarkers
lifetime intellectual activity bing → amyloid burden*		0.008	0.041	0.839
current intellectual activity → amyloid burden*		0.007	0.042	0.866
current physical activity → amyloid burden*		0.046	0.042	0.270
lifetime intellectual activity → glucose metabolism		0.044	0.042	0.299
current intellectual activity → glucose metabolism		0.045	0.044	0.300
current physical activity → glucose metabolism		−0.023	0.043	0.590
lifetime intellectual activity → hippocampal volume		−0.019	0.040	0.627
current intellectual activity → hippocampal volume		0.074	0.041	0.072
current physical activity → hippocampal volume		0.014	0.041	0.728
Paths to the Global Cognition Variable
lifetime intellectual activity → z(global)	Yes	0.360	0.037	1.44E-22
current intellectual activity → z(global)	Yes	0.092	0.038	0.015
current physical activity → z(global)		0.034	0.038	0.364
amyloid burden*→ z(global)	Yes	0.086	0.040	0.032
glucose metabolism → z(global)	Yes	0.200	0.041	8.29E-07
hippocampal volume → z(global)	Yes	0.192	0.043	7.30E-06

^*Coded as -ln(Amyloid Burden).