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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Immunol Rev. 2013 Jan;251(1):80–96. doi: 10.1111/imr.12021

Fig. 6. Variations in ‘secondary circuits’.

Fig. 6

Here we present cartoon version of circuits representing: (A) Collective responses in which simultaneously primed cells of different (T-B) or similar (T-T) members of the adaptive immune response form a circuit that results in the amplification or collective differentiation of the response. (B) Tissue repriming responses as an example of reciprocal stimulation of adaptive cells by innate and innate by adaptive. (C) Competitive circuits in which the flux through one circuit likely negates interactions in a second circuit.