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. 2013 Jan;23(1):14–24. doi: 10.1089/thy.2012.0374

Table 2.

Unexpected Development of Hyperthyroidism Caused by Thyroid-Stimulating Autoantibodies in Hypothyroid Patients with Hashimoto's Thyroiditis Lacking Thyrotropin-Blocking Autoantibodies

 
 
Thyroid autoantibodies
Sex, age (years) Status TBAb TSAb TgAb TPOAb
F, 23 Hypo     3202 802
  Hyper Neg 1900 6402 3202
  Eu Neg 100 802 Neg
F, 53 Hypo     6402 3202
  Hyper Neg 780 6402 3202
  Eu Neg 96 1602 802
  Hyper Neg 1050 6402 3202
  Eu Neg 100 1602 802
F, 28 Hypo     (80) (160)
  Hyper Neg (900) 6402 1602
F, 42 Hypo     pos pos
  Hyper     802 1602
F, 38 Hypo     6402 6402
  Hyper Neg   12802 12802
F, 80   Neg 1583a   1300 units

First five patients from Ref. (31); sixth patient from Ref. (34). Values for all thyroid autoantibodies are TSAb μU/mL bovine thyrotropin (bTSH) equivalent; Neg, negative (undetectable); blanks, data not reported. TgAb and TPOAb are reciprocal titers. Bold indicates positive values for TSAb or TBAb, or increased values for TgAb or TPOAb after LT4. Parentheses indicate values estimated from the figures in Ref. (31) for TgAb, TPOAb, or TSAb activity.

a

% Stimulation of cAMP.