Table 3.

Thyroid Autoantibodies at the Time Hypothyroidism Developed in Graves' Patients Treated with Anti-Thyroid Drugs

	Autoantibodies
Sex, age (years)	TSAb	TBAb	TgAb	TPOAb	Ref.
Group I
F, 35	80	85	640	72,900	(37)
F, 20	80	83	212	212	(36)
F, 24	358	57		27	(36)
F, 18	68	97		212	(36)
F, 39	102	87	24	212	(36)
M, 36	97	92	22	210	(36)
F, 62	104	90		212	(36)
F, 42	1252	55	22	26	(36)
M, 29	101	98		212	(36)
F, 55a					(32)
B	576	Neg	Neg	Neg
Eu	275	18
A	593	48
F, 40					(38)
B	295	58	100	6400
Eu	76	97	100	400
A	484	45	400	1600
F, 54b	313	82	Neg	500	(5)
F, 40					(33)
B	1625	2
A	∼150	∼98
F, 48					(33)
B	800	5
A	∼200	∼98
Group II
F, 48	<140	10.0	>104	>105	(37)
F, 54	101	−2.0	>104	>106	(37)
F, 30	902	6.8	210	212	(36)
F, 52	182	−17.4	28	212	(36)
F, 47	432	−12.4	28	212	(36)
F, 25	279	−4.0	24	212	(36)
F, 25	190	6.7		212	(36)
F, 33	11,429	ND		210	(36)
F, 27	312	−10.9	24	28	(36)
F, 42	1290	22.0	26	210	(36)

Group I patients: hypothyroidism due to the appearance of TBAb; Group II patients: hypothyroidism due to thyroiditis. Where available, data are included before (B), when euthyroid (Eu), and after (A) development of hypothyroidism. Values for all thyroid autoantibodies are TSAb μU/mL bTSH equivalent; Neg, negative (undetectable); blanks, data not reported; ND, TSAb too high for reliable TBAb measurement. TgAb and TPOAb are reciprocal titers. Bold indicates values positive for TSAb or TBAb.

^aPatient initially hypothyroid without detectable TBAb subsequently fluctuated between hyper- and hypothyroidism with associated TSAb and TBAb (32).

^bPatient from whom monoclonal TBAb and TSAb were derived (5).