Table 4.
Analysis of the effect of prognostic factors on overall survival using the multivariable Cox model.
| HR | CI | Pa | |
|---|---|---|---|
| Age, years | |||
| ≥10 versus <10 | 1.7 | (1.1,2.6) | 0.018 |
| Histologicalsubtype | |||
| MPNST versus other | 2.3 | (1.5,3.7) | <0.001 |
| Synovial sarcoma versus other | 0.7 | (0.4,1.2) | |
| Tumour site | |||
| Head–neck versus extremity | 2.0 | (1.1,3.7) | 0.001 |
| Other versus extremity | 2.7 | (1.6,4.5) | |
| Tumour size, cm | |||
| >5 versus ≤5 | 2.5 | (1.3,4.6) | 0.006 |
| Delayed surgery | |||
| Not performed versus complete | 4.3 | (2.4,7.5) | <0.001 |
| Not specified versus complete | 3.3 | (1.1,9.6) | |
| Incomplete versus complete | 2.2 | (1.1,4.3) | |
| Radiotherapy | |||
| Not performed versus performed | 1.8 | (1.2,2.8) | 0.003 |
| Response to chemotherapy | |||
| Minor versus major | 2.1 | (1.1,3.7) | <0.001 |
| None versus major | 3.2 | (1.9,5.1) |
HR, hazard ratio; CI, 95% confidence interval; HR is an estimate of the increase (if >1) or decrease (if <1) in the risk associated with a covariate category versus the reference category (assumed to carry a risk of one). The larger the HR, the stronger the association between the variable and mortality. Confidence intervals not including the value of one indicate a significant difference towards the reference category.
MPNST, malignant peripheral nerve sheath tumour.
a
Two-sided Wald test p value.