Table 2.
Biochemical parameters of alloxan-induced diabetic rabbits after 28 days treatment with drug and P. vestitum extract (N = 7).
| Parameters | Diabetic control | Std | Pv ext |
|---|---|---|---|
| Glucose (mg/dL) | 250.1 ± 7.8 | 216.5 ± 4.7* (−13.43%) |
202.7 ± 7.7* (−18.95%) |
| Cholesterol (mg/dL) | 46.6 ± 6.3 | 30.5 ± 7.3* (−34.5%) |
19.3 ± 7.3* (−58.5%) |
| Triglyceride (mg/dL) | 81.7 ± 10.9 | 60.4 ± 8.2* (−26.07%) |
44.0 ± 6.5* (−46.14%) |
| LDL (mg/dL) | 39.2 ± 7.5 | 29.0 ± 3.8* (−26.02%) |
16.5 ± 5.8* (−57.90%) |
| HDL (mg/dL) | 14.1 ± 5.6 | 22.7 ± 5.4* (+60.99%) |
26.8 ± 5.6* (−90.07%) |
| GPT (U/L) | 76.71 ± 4.29 | 54.42 ± 2.09* (−29.05%) |
34.0 ± 2.7* (−55.67%) |
| ALP (U/L) | 51.14 ± 3.26 | 38.8 ± 3.4* (−24.12%) |
19.8 ± 3.2* (−61.28%) |
| Bilirubin (mg/dL) | 2.23 ± 0.14 | 1.74 ± 0.09* (−25.32%) |
1.03 ± 0.15* (−55.7%) |
| Creatinine (mg/dL) | 2.08 ± 0.9 | 1.36 ± 0.6* (−34.61%) |
1.24 ± 0.5* (−40.38%) |
Std: standard glibenclamide group and Pv ext: P. vestitum extract group. Values are means and standard error of means of 7 replicates. *The mean difference is significant at P < 0.05 level. Values in parentheses indicate percent changes from the diabetic control group.