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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Free Radic Biol Med. 2012 Sep 16;54:105–112. doi: 10.1016/j.freeradbiomed.2012.09.005

Fig. 1.

Fig. 1

IPC-I/R protocol. Mouse hearts were Langendorff-perfused with Krebs-Henseleit buffer (oxygenated with 95% O2/5% CO2 and maintained at pH 7.4) at a constant pressure of 100 cm of water at 37 °C in the dark. After equilibrium perfusion or IPC (4 cycles of 5 min of ischemia and 5 min of reperfusion), mouse hearts were subjected to 20 min of no-flow ischemia followed by 90 min of reperfusion. Drug administration (10 μM ODQ or 1 μM KT5823) is illustrated for each IPC-I/R protocol.