Table 1.
Serum parameters and body weights in CKD mice and sham controls under NP and HP feeding conditions
| Study groups | n | Body weight (g) | BUN (mg/dL) | Pi (mg/dL) | Ca (mg/dL) | PTH (pg/mL) | ALP (U/Liter) |
|---|---|---|---|---|---|---|---|
| Sham/NP | 5 | 26.2 ± 0.7 | 22.4 ± 1.0 | 9.1 ± 0.8 | 10.5 ± 0.2 | 59.9 ± 8.3 | 58.4 ± 6.5 |
| Sham/HP | 6 | 27.8 ± 1.0 | 21.3 ± 0.8 | 10.1 ± 0.6 | 10.7 ± 0.1 | 80.6 ± 15.2 | 50.0 ± 12.9 |
| CKD/NP | 6 | 23.1 ± 0.5a,b | 70.0 ± 4.2a,b | 10.2 ± 0.4 | 11.7 ± 0.2a,b | 283.8 ± 46.6a,b | 146.7 ± 37.7a,b |
| CKD/HP | 4 | 21.8 ± 0.8a,b | 49.0 ± 3.4a,b,c | 9.7 ± 0.4 | 10.5 ± 0.2c | 428.6 ± 39.5a,b,c | 141.0 ± 19.4a,b |
CKD, chronic kidney disease; NP, normal 0.5% phosphate diet; HP, high 0.9% phosphate diet; BUN, blood urea nitrogen; Pi, phosphorus; Ca, calcium; PTH, parathyroid hormone; ALP, alkaline phosphatase.
aThere is a statistically significant difference compared with the sham/NP group (P< 0.05).
bThere is a statistically significant difference compared with the sham/HP group (P< 0.05).
cThere is a statistically significant difference compared with the CKD/NP group (P< 0.05).